U.S. Approves Drugs to Treat Severe Alopecia

This week, the US Food and Drug Administration (FDA) approved a drug for severe alopecia, a disease that causes hair loss or hair loss and affects more than 300,000 people annually in the United States alone. Manufactured by the pharmaceutical company Eli Lilly and marketed under the name Olmiant, baricitinib belongs to a class of drugs that block inflammation and is the first oral tablet to treat alopecia areata.

O Baricitinib It has already been approved for the treatment of rheumatoid arthritis and has been extended to patients with severe covid-19.

The FDA approvals for drugs for the treatment of severe alopecia are: Two clinical trials involving 1,200 adults with alopecia areataA disease in which the immune system attacks hair follicles, causing temporary or permanent loss of hair or fur in certain areas of the body.

For each clinical trial Participants were divided into three groups: One-third received placebo, one-third received a daily dose of 2 mg, and one-third received a daily dose of 4 mg. After 36 weeks, the following results were obtained.

  • Almost 40% of the highest dose patients experienced 80% hair growth, compared to about 23% of low dose patients and 5% of placebo people.
  • Approximately 45% of people who took 4 mg had significant hair growth in certain areas, especially the eyebrows.

The most common side effects recorded during clinical trials were upper respiratory tract infections, headaches, acne, high cholesterol, and increased presence of an enzyme called creatine kinase.

Other treatments have been tested to treat alopecia areata, but none have been approved by the FDA.

“Access to safe and effective treatment options is very important for a significant number of Americans affected by severe alopecia.”, An FDA official said. “This move helps address the critical needs of patients with this disease,” Kendal Marcus concludes.

Alopecia is a disease that occurs when the immune system attacks the hair follicles. Hair loss or hair loss can be temporary or even permanent and can cause great mental distress.

Recently, this illness Actress Jada Pinkett Smith or Democratic Ayanna Pressley Revealed that they have it.

Will Smith and Jada Pinkett Smith, Oscar, March 27, 2022. (AP)

Smith’s aggression against Chris Rock during the Oscar ceremony also indirectly contributed to the promotion of this health problem. Locke joked about Will Smith’s wife, Jada. The actor didn’t like it, so he went on stage and slapped the comedian.

In general, alopecia can affect both men and women, but it is more common in men. The disease usually develops before the age of 30, but can occur at any point in life, including children and adolescents.

There are several types of alopecia, but two are considered to be the most common.

  • Alopecia areata – Hair loss or hair loss can occur anywhere on the body, including the scalp, beard, and armpits.
  • Androgenetic alopecia – Related to hormonal or genetic problems, mainly affecting men and related to baldness.

Other types of alopecia can be identified, but less frequently.

  • Traumatic alopecia – Caused by head trauma or by mechanical traction on the hair, a particular hairstyle that can cause hair loss.
  • Seborrheic alopecia – Seborrheic dermatitis, caused by inflammation that affects the scalp and causes increased oiliness, dandruff and itching.

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