Ministry of Health analyzes vaccine acquisition process to define smallpox immune strategy

With the threat of Monkeypox spread, Ministry of Public Health Already evaluating the acquisition process vaccinationNext, we will define an immunization strategy in Brazil. The disease was eradicated in the 1970s, so there is no immune stock in stock in this country.

World Health Organization (World Health Organization) because there is no unique vaccine to protect against monkeypox (monkeypox)WHO) We recommend an immune agent that works against traditional smallpox (smallpox) as long as it is the latest 2nd or 3rd generation ()It is not duplicated in the human body). This type of drug has been proven to be 85% effective against monkeypox, guaranteeing its substance.

Vaccines that are already highly regarded are used in some countries. Called Jynneos (USA), Imvamune (Canada), or Imvanex (Europe), manufactured by the Danish Institute Bavarian Nordic. The immune system was approved by the US Food and Drug Administration (FDA) in 2019 and by the European Medicines Agency (EMEA) in 2013.

However, in Brazil, this product is still available from the Brazilian Health Regulatory Agency (Ambisa).

Before being released for use in the country, all new drugs or vaccines are available from the Brazilian Health Regulatory Agency (Ambisa). This is a normal procedure, but so far, authorities have informed that there is no vaccine or drug request for monkeypox in Brazil. The initiative must come from a pharmaceutical laboratory.

Jynneos cannot replicate in the human body, are less likely to cause side effects than traditional vaccines, and have proven effective in eliciting a strong immune response. People who have not been previously vaccinated against smallpox should be vaccinated twice at 28-day intervals. However, the term of protection is still unknown.

Despite being cited, vaccines are not widely available. In the face of an increasing number of monkeypox cases worldwide, Bavarian Nordic has announced increased production of immune agents. However, the Ministry of Health does not say which vaccines are being analyzed for purchase.

This week, Health Oversight Secretary Arnaldo de Medeiros of the Ministry of Health reported that the federal government is negotiating to buy an immune agent that protects against smallpox, but did not provide further details. did.The statement was made in an interview with the portal Big city.

Meetings with manufacturers are also being held, according to Medeiros, and the acquisition is mediated by the Pan American Health Organization (PAHO). Dose is expected to reach the country between the third and fourth quarters of this year, he said.

Who can get immunity

The World Health Organization (WHO) does not recommend mass vaccination of monkeypox populations. According to the entity, only priority groups, such as laboratory workers exposed to the virus and those in close contact with infected people, should receive the immune system.

Also, according to WHO, in addition to vaccination of specific groups, measures to manage and diagnose the disease can prevent a global outbreak.

What are the symptoms of monkeypox?

Symptoms, to a lesser extent, are similar to those seen in older patients with smallpox. The first 5 days are fever, headache, muscle aches and back pain. Then there are eruptions, lesions, pustules, and finally scabs on the face, palms, and soles of the feet.

How will it be sent?

Early infections are due to direct contact with lesions of the infected animal’s blood, body fluids, skin or mucous membranes. Secondary human-to-human transmission results from infected secretions from the airway, lesions on the infected person’s skin, or close contact with body fluids or substances recently contaminated from the patient’s wounds. There is a possibility.

Health risks

In expert opinion, monkeypox should not have the same dimensions as covid-19. According to scientist Ester Sabino, a professor at the University of Sao Paulo (USP) and leader of the group responsible for the initial sequencing of the virus in Brazil, the virus, which causes smallpox in monkeys, is as airborne as the coronavirus. Does not cause infection. ..

— Monkeypox requires very close contact for people to become infected. Therefore, monkeypox probably will not have the same dimensions as Covid, “he said in a statement. Interview with newspaper OEstadode S. Paulo..

Cases confirmed in Brazil

Currently, in Brazil, 3 cases have been confirmed in São Paulo, 1 case in Rio Grande do Sul, and 1 case in Rio de Janeiro, for a total of 5 cases. Eight are still under investigation. One death under investigation in Minas Gerais was abandoned by the Ezekiel Diaz Foundation this Wednesday (15) due to monkeypox. This is a 41-year-old man with no travel history and no contact with suspected or confirmed cases of illness. The cause of death is still under investigation.

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